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The ImageStream combines both imaging and flow cytometry with multiple magnifications, making it ideally suited for the screening of heterogeneous populations (various cell types) and/or heterogeneous samples (e.g. blood samples, exosomes, etc.)

Examples of its unique capabilities include:

  • Visual verification of every cell

  • Nuclear translocation

  • IReceptor co-localization

  • Cellular activation and apoptosis in cell mixtures

  • Morphological cell classification of heterogeneous mixtures

  • Biological consequences of cell-cell interactions

  • Analysis of exosomes or nanoparticles interacting with cells

An overview of some of the possibilities with the ImageStream can be found below

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The ImageStream allows us to visualize and gate two different cell populations that have varying emission wavelengths using a 40x magnification: CT-26 mouse colon carcinoma cells transduced with lentiviral particles expressing GFP and 4T1 mouse breast cancer cells transduced with lentiviral particles expressing RFP.

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